Previously, Proactiv was owned by:
- Rodan and Fields: Dermatologists Kathy Fields and Katie Rodan founded Proactiv in 1994.
- Nestlé: In 2000, Nestlé acquired a majority stake in Proactiv from Rodan and Fields.
- EQT AB: In 2016, EQT AB purchased Nestlé's stake in Proactiv.
- Galderma: In 2022, Galderma acquired Proactiv from EQT AB.
- Taro Pharmaceutical Industries: In 2022, Taro Pharmaceutical Industries acquired Proactiv from Galderma.