What are Restylane and Perlane?
The Restylane family of dermal filler products includes Restylane and Perlane. Both are cosmetic dermal fillers that replace lost volume and restore youthful contours to the skin to smooth away moderate to severe facial wrinkles and folds, such as the lines from your nose to the corners of your mouth (nasolabial folds), and from the corners of the mouth downward (marionette lines). These dermal fillers can also be used to replenish volume in the lips and to help smooth the lines which radiate from the lips.
How do I choose between Restylane and Perlane?
You don't have to. In clinical trials, Restylane and Perlane dermal fillers were used in the same patients. The hyaluronic acid in both collagen injections is made by the same biotechnical process. The difference is in the gel particle size. Perlane gel particles are larger and designed for deeper injection than Restylane. Your practitioner will decide which dermal filler is right for you.
How does my practitioner know when to use Restylane and Perlane?
Your practitioner will decide which dermal filler is right for you based on an evaluation of facial wrinkled and folds.
How long do Restylane products last?
Restylane products are proven to deliver long-lasting results. Restylane lasts about six months. Perlane lasts at least six months, in a majority of patients.
Are Restylane and Perlane FDA approved?
Yes. They are approved by the FDA for the treatment of moderate to severe facial wrinkles and folds, like the ones from your nose to the corners of your mouth. Ask your practitioner whether this cosmetic procedure is right for you.
What is the history of Restylane?
Restylane has been used in over 1.4 million treatments in the U.S. and is available in more than 70 countries. It is the most-studied cosmetic dermal filler in the world with dozens of publications in medical literature. Clinical studies showed no significant differences in the safety of Restylane and Perlane.
What should patients do prior to treatment?
Restylane and Perlane require no pretesting, but you should take a few precautions before being treated. Avoid using aspirin, nonsteroidal anti-inflammatory medications, St. John's Wort, or high doses of Vitamin E supplements prior to treatment, because these may increase bruising or bleeding at the injection site. Also, if you have previously suffered facial cold sores, discuss this with your practitioner who may prescribe a medication to minimize recurrence.
How are Restylane products administered?
Restylane and Perlane dermal fillers are administered by injection into the skin at the treatment site. Before treatment talk to your practitioner about pain management.
Is any of the material left in the skin after it has dissolved?
No. Over time, Restylane and Perlane products are broken down and eliminated by the body.
What are Restylane and Perlane products made of?
Restylane is a cosmetic dermal filler made from hyaluronic acid that has been modified slightly to last longer than the body's hyaluronic acid. In the human body natural hyaluronic acid provides volume and fullness to the skin.
How are Restylane products different than other hyaluronic acid-based products?
Restylane and Perlane contain no animal proteins. This limits any risk of animal-based disease transmission or allergic reaction. You should not use Restylane or Perlane if you have allergies to microorganisms known as gram-positive bacteria.
How do Restylane and Perlane collagen dermal fillers differ from Botox Cosmetic?
Botox Cosmetic and Restylane are used to correct wrinkles in different ways, Restylane and Perlane are natural, cosmetic fillers injected into the skin, adding volume to smooth wrinkles and folds in the lower face. In contrast, Botox is a natural, purified protein that temporarily relaxes the muscles that cause lines in the upper face. In general, Botox is used to treat wrinkles in the upper half of the face. And Restylane/ Perlane is used to treat the lines and folds in the lower half of the face.
What should patients expect after a dermal filler treatment?
Often redness and swelling occur. This can last up to seven days, but usually about three days. You may have some bruising, which can be covered with make-up.
